Find a TherapistReady to get started?Ready toget started?Add your email to continueEmailGet startedBy submitting your email, you agree to receive reminders and marketing communications.

Mental Health Conditions

Ready to get started?Ready toget started?Add your email to continueEmailGet startedBy submitting your email, you agree to receive reminders and marketing communications.

Ready to get started?

Ready toget started?

Add your email to continue

Get started

By submitting your email, you agree to receive reminders and marketing communications.

Mental Health HomepageConditions LibraryConditions CategoryConditions CategoryWhy Does Depression Make it Difficult to Function?

Table of Contents:OverviewDefining AnhedoniaDiagnosing Clinical DepressionWhy Andheonia Makes It Hard To FunctionGetting Help for Loss of InterestIf You’re In CrisisThere’s Hope

DepressionRead Time: 6 Minutes

Published On: August 24, 2018

Reviewed On: August 24, 2018

Updated On: November 1, 2023

OverviewSometimes depression can sneak up on us, seeping into our lives without detection until it hits hard weeks, months, or even years later. Other times it shows up suddenly, like a heavy, wet blanket that has been thrown on top of us.Either way, one of depression’s hallmark features is our loss of interest in seeminglyeverything, whether it’s a favorite pastime or the people closest to you — it can make getting out of bed at all nearly impossible. The world, which once seemed round, flattens out. We’re no longer having any fun and sometimes it’s downright hard to function.The culprit? In the case of clinical depression, usually it’s a symptom referred to asanhedonia.

Overview

Sometimes depression can sneak up on us, seeping into our lives without detection until it hits hard weeks, months, or even years later. Other times it shows up suddenly, like a heavy, wet blanket that has been thrown on top of us.

Either way, one of depression’s hallmark features is our loss of interest in seeminglyeverything, whether it’s a favorite pastime or the people closest to you — it can make getting out of bed at all nearly impossible. The world, which once seemed round, flattens out. We’re no longer having any fun and sometimes it’s downright hard to function.

The culprit? In the case of clinical depression, usually it’s a symptom referred to asanhedonia.

Defining Anhedonia

To help lift us out of the gray, people in our lives often invite us to go out and exercise or socialize to feel better. Due to anhedonia’s effect on ourinternal reward systems, it’s not always possible to act on these well-meaning offers. We simply don’t have control over our loss of interest, and unfortunately, not being able to engage in pleasurable activities creates a feedback loop.

“It can become a vicious cycle, since anything you could do to improve your mood no longer seems to help, and may sometimes even worsen it since you notice the difference and lack of benefit,” says Dr. Jean Kim, clinical assistant professor of psychiatry at George Washington University. “Anhedonia can be one of the most serious signs of depression.”

Diagnosing Clinical DepressionAnhedonia is a symptom of several mental illnesses and neuropsychiatric disorders, includingschizophrenia, substance use disorders, some eating/feeding disorders, and even Parkinson’s disease.Most commonly though, it’s associated with depression. According to theDiagnostic and Statistical Manual of Mental Disorders, which is used to diagnose mental illness, anhedonia is indeed one of two “must-have” symptoms in order to determine clinical depression.“[Anhedonia is] actually one of the key points that distinguish feeling sad or low or having the blues…from a diagnosable disorder,” says Dr. Simon Rego, chief psychologist at Montefiore Medical Center and associate professor of psychiatry and behavioral sciences at Albert Einstein College of Medicine in New York. “It makes it very difficult to function in either your social life, your work or school life, or in your home, family life.”

Diagnosing Clinical Depression

Anhedonia is a symptom of several mental illnesses and neuropsychiatric disorders, includingschizophrenia, substance use disorders, some eating/feeding disorders, and even Parkinson’s disease.

Most commonly though, it’s associated with depression. According to theDiagnostic and Statistical Manual of Mental Disorders, which is used to diagnose mental illness, anhedonia is indeed one of two “must-have” symptoms in order to determine clinical depression.

“[Anhedonia is] actually one of the key points that distinguish feeling sad or low or having the blues…from a diagnosable disorder,” says Dr. Simon Rego, chief psychologist at Montefiore Medical Center and associate professor of psychiatry and behavioral sciences at Albert Einstein College of Medicine in New York. “It makes it very difficult to function in either your social life, your work or school life, or in your home, family life.”

Why Andheonia Makes It Hard To Function

As for why anhedonia makes it hard to function, we need to look at the brain’s reward system. Though, exactly how anhedonia works or where the process goes awry is still a complicated question researchers haven’t quite figured out the answer to.

In brief, asScience Alertdescribes, “pleasure is the feeling we get that drives us to seek out a stimulus.” As we find pleasure, our brain’s neurochemistry activates a complex system that drives us to repeat what makes us feel good. For example, we discover that cookies taste awesome, so we go back to the cookie jar over and over.”

When we lose interest in activities, several facets of this process may be disrupted. Somerecent researchsuggests that our mPFC “traffic cop” has essentially taken a vacation and decreases its activity level. Other theories point to an imbalance in neurotransmitters, particularly dopamine, one of the “feel good” chemicals in our brain. Additionalresearchidentifies that “GABA (an inhibitory neurotransmitter), glutamate (an excitatory neurotransmitter), serotonin, and opioids may also play their part” in the process.

Long story short,MedicalNewsTodayperhaps sums up anhedonia more colloquially: “Something [is] amiss as far as motivation, anticipation, and reward are concerned. For people with anhedonia, the reward process has come unhinged.”

Getting Help for Loss of InterestIf any of this sounds familiar and you’ve lost of interest in previously enjoyed activities, reach out for help.Clinical depressionwith anhedonia, if left untreated, can have serious consequences that make it difficult to function in our social, work, and school lives. Know this isn’t your fault — depression is an illness.“You can’t get your blood drawn and they say, ‘Oh, this marker is out of range. That’s why you have depression.’ So it’s easy then to dismiss it or minimize it as all in your head or stigmatize it….All that is simply untrue,” says Simon Rego. “It’s important to recognize it’s a real medical condition and…it’s really important, especially if it’s persisting for at least a couple of weeks, to reach out and get help from a professional.”Amental health professional— or your family doctor if that’s more comfortable — can address your depression symptoms. If you’re having trouble reaching out for support, ask a loved one if they will help you search for a service provider, make the call, or even take you to your first appointment. Though we may not know everything about what causes depression, it can absolutely be treated. If you’re looking for help with depression symptoms, consider Talkspace’s online therapy andtelehealth psychiatry services— a convenient way to start feeling better.“Depression, once diagnosed, can be treated with psychotherapy to address life stressors, patterns, and behaviors, and sometimes medication to address the underlying neurobiology in your brain that is triggering depressive symptoms,” says Dr. Jean Kim. “Other helpful ways to manage depressive moods (usually in their milder stages) include reaching out to your support network,exercise, and decreasing life stressors whenever possible.”Rego also recommends making sure we take care of the basics. “Keep yourself in a daily rhythm where you try to maintain as best you can a constant wake time, a good bedtime, and try to keep yourself engaged in things, even if they don’t seem pleasurable,” he says.

Getting Help for Loss of Interest

If any of this sounds familiar and you’ve lost of interest in previously enjoyed activities, reach out for help.Clinical depressionwith anhedonia, if left untreated, can have serious consequences that make it difficult to function in our social, work, and school lives. Know this isn’t your fault — depression is an illness.

“You can’t get your blood drawn and they say, ‘Oh, this marker is out of range. That’s why you have depression.’ So it’s easy then to dismiss it or minimize it as all in your head or stigmatize it….All that is simply untrue,” says Simon Rego. “It’s important to recognize it’s a real medical condition and…it’s really important, especially if it’s persisting for at least a couple of weeks, to reach out and get help from a professional.”

Amental health professional— or your family doctor if that’s more comfortable — can address your depression symptoms. If you’re having trouble reaching out for support, ask a loved one if they will help you search for a service provider, make the call, or even take you to your first appointment. Though we may not know everything about what causes depression, it can absolutely be treated. If you’re looking for help with depression symptoms, consider Talkspace’s online therapy andtelehealth psychiatry services— a convenient way to start feeling better.

“Depression, once diagnosed, can be treated with psychotherapy to address life stressors, patterns, and behaviors, and sometimes medication to address the underlying neurobiology in your brain that is triggering depressive symptoms,” says Dr. Jean Kim. “Other helpful ways to manage depressive moods (usually in their milder stages) include reaching out to your support network,exercise, and decreasing life stressors whenever possible.”

Rego also recommends making sure we take care of the basics. “Keep yourself in a daily rhythm where you try to maintain as best you can a constant wake time, a good bedtime, and try to keep yourself engaged in things, even if they don’t seem pleasurable,” he says.

If You’re In CrisisSomeevidencesuggests there is a strong link between anhedonia and an increased risk of suicide. If you are having thoughts of killing or harming yourself, it’s an emergency. Reach out to a loved one, call 911, go to the emergency room, or call theNational Suicide Prevention Lifelinefor immediate help. Your life matters, it can get better, and you’re needed here, alive.

If You’re In Crisis

Someevidencesuggests there is a strong link between anhedonia and an increased risk of suicide. If you are having thoughts of killing or harming yourself, it’s an emergency. Reach out to a loved one, call 911, go to the emergency room, or call theNational Suicide Prevention Lifelinefor immediate help. Your life matters, it can get better, and you’re needed here, alive.

There’s Hope

If you need a little inspiration in the meantime, try the wise words of poet Aberjhani:

“Even when muddy your wings sparkle bright wonders that heal broken worlds.”

Renee FabianRenée Fabian is a Los Angeles-based journalist and editor. She has written for Talkspace, The Washington Post, and Healthline, among others, and is currently an editor at The Mighty. Renée holds a master’s degree in journalism and will complete a master’s degree in psychology in fall 2019.

Renée Fabian is a Los Angeles-based journalist and editor. She has written for Talkspace, The Washington Post, and Healthline, among others, and is currently an editor at The Mighty. Renée holds a master’s degree in journalism and will complete a master’s degree in psychology in fall 2019.

Share

Effective and affordable mental health treatmentGet Started

Effective and affordable mental health treatment

Related Articles About DepressionView all articlesDepressionOctober 23, 2024Depression in Nurses: A Mental Health Crisis in HealthcareDepressionOctober 23, 2024Fatherhood Depression: Breaking the Silence on Depressed DadsDepression, ParentingSeptember 18, 2024What to Do if Your Teenager is Making You Feel DepressedDepressionSeptember 18, 2024Post-Weaning Depression: Recognize the Signs & Find SupportDepressionSeptember 18, 2024How to Think Positive When Depressed: Techniques for a Brighter OutlookDepressionSeptember 18, 2024Have You Fallen Out of Love, or Are You Depressed?DepressionJuly 24, 2024How to Prevent Postpartum DepressionDepressionJuly 24, 2024How to Explain Depression to SomeoneDepressionJuly 24, 2024Are There Stages of Depression?DepressionJune 21, 2024Can Adderall Cause Depression?

Related Articles About DepressionView all articles

DepressionOctober 23, 2024Depression in Nurses: A Mental Health Crisis in HealthcareDepressionOctober 23, 2024Fatherhood Depression: Breaking the Silence on Depressed DadsDepression, ParentingSeptember 18, 2024What to Do if Your Teenager is Making You Feel DepressedDepressionSeptember 18, 2024Post-Weaning Depression: Recognize the Signs & Find SupportDepressionSeptember 18, 2024How to Think Positive When Depressed: Techniques for a Brighter OutlookDepressionSeptember 18, 2024Have You Fallen Out of Love, or Are You Depressed?DepressionJuly 24, 2024How to Prevent Postpartum DepressionDepressionJuly 24, 2024How to Explain Depression to SomeoneDepressionJuly 24, 2024Are There Stages of Depression?DepressionJune 21, 2024Can Adderall Cause Depression?

DepressionOctober 23, 2024Depression in Nurses: A Mental Health Crisis in Healthcare

Featured Image

DepressionOctober 23, 2024Fatherhood Depression: Breaking the Silence on Depressed Dads

Depression, ParentingSeptember 18, 2024What to Do if Your Teenager is Making You Feel Depressed

DepressionSeptember 18, 2024Post-Weaning Depression: Recognize the Signs & Find Support

DepressionSeptember 18, 2024How to Think Positive When Depressed: Techniques for a Brighter Outlook

DepressionSeptember 18, 2024Have You Fallen Out of Love, or Are You Depressed?

DepressionJuly 24, 2024How to Prevent Postpartum Depression

DepressionJuly 24, 2024How to Explain Depression to Someone

DepressionJuly 24, 2024Are There Stages of Depression?

DepressionJune 21, 2024Can Adderall Cause Depression?

If you are in a life threatening situation – don’t use this site. Call 988 or useto get immediate help.

Therapy may be free for you