Table of ContentsView AllTable of ContentsHealth BenefitsSide EffectsDosage and PreparationPrecautionsDrug Interactions and WarningsAlternatives
Table of ContentsView All
View All
Table of Contents
Health Benefits
Side Effects
Dosage and Preparation
Precautions
Drug Interactions and Warnings
Alternatives
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Passion flower (passiflora incarnata) is an herbal supplement used historically in treating anxiety, insomnia, seizures, and hysteria. A perennial climbing vine native to southeastern North America, passion flower is now grown throughout Europe.
Theherbal supplementis composed of the flowers, leaves, and stems of the plant. When used in complementary medicine, passion flower is available as infusions, teas, liquid extracts, and tinctures.
At a GlancePassion flower has shown some promise in alleviating some mental health conditions, including anxiety and depression. However, it’s important to talk to your doctor before trying it. There is a possibility of drug interactions, so always tell your doctor about other medications or supplements you are taking. Most importantly, remember that passion flower isn’t a replacement for proven treatments like medication and therapy. Discussing your symptoms with your doctor is the best way to get the right treatment for you.
At a Glance
Passion flower has shown some promise in alleviating some mental health conditions, including anxiety and depression. However, it’s important to talk to your doctor before trying it. There is a possibility of drug interactions, so always tell your doctor about other medications or supplements you are taking. Most importantly, remember that passion flower isn’t a replacement for proven treatments like medication and therapy. Discussing your symptoms with your doctor is the best way to get the right treatment for you.
Verywell / Nusha Ashjaee

Does Passion Flower Have Health Benefits?
While you might hear a lot about the purported benefits of an herbal remedy, that doesn’t always mean that the research backs up the claims. That’s why it’s important to note that the safety and effectiveness of passion flower have not been adequately studied. However, there are reports that this herbal supplement may have a few health benefits.
It May Help Reduce Anxiety
Evidence from limited animal and human research suggests that the supplement may be useful in treating anxiety, insomnia, andnervous disorders.
Passion flower’s anxiolytic effects are thought to be due to its impact onneurotransmitters, including GABA anddopamine. One study found that passion flower extract led to significant increases in dopamine levels.
A 2018 review of the use of various herbal medicines in the treatment of psychiatric conditions suggested that high-quality evidence was available supporting the use of passion flower to relieve anxiety disorders.
Some Variants May Relieve Stomach Upset
Some research also indicates that certain types of passion flower might be useful for relieving stomach problems, including ulcers. One animal study found that passion flower extract helped relieve stomach ulcers in rats. However, more research is needed to determine if passion flower might have the same effect in humans.
Other Possible Uses
Passion flower is also sometimes used as a supplement treat:
However, it is important to note that while passion flower is sometimes utilized or promoted for these purposes, there is a lack of evidence to support these uses. The National Center for Complementary and Integrative Health, a division of the National Institutes for Health, states that there is not enough research to demonstrate that passion flower can help treat cardiac issues, stress, menopause, pain, burns, hemorrhoids, or ADHD.
More rigorous scientific studies are needed to make firm conclusions about the effectiveness of passion flower for thetreatment of anxiety problemsand other health conditions.
Passion Flower Can Have Side Effects
Side effects have been rarely reported for passion flower but may include:
When taking passion flower, ensure you don’t drive or operate heavy machinery until you know how it affects you.
In general, passion flower is considered safe and nontoxic.However, the U.S. Food and Drug Administration (FDA) does not regulate the production of herbs and supplements.
One small study indicated that passion flower might be associated with pregnancy complications. Further research is needed to better understand this potential risk.
While some research suggests that passion flower is generally safe, it’s important to remember that most herbs and supplements are not thoroughly tested, and there is no guarantee regarding the ingredients or safety of the products.
Passion Flower Dosage and Preparation
So, just how much passion flower should you take? And how should you take it? Since passion flower is an herbal remedy, there are no recommended amounts. However, some research has suggested some different dosages based on how you choose to consume it.
Passion flower can be consumed as an infusion, tea, liquid extract, or tincture. It is important to stress that these dosages are not prescriptions but merely suggested guidelines.
There is not enough scientific evidence to support the use of passion flower in children.
Precautions When Taking Passion Flower
The same advice applies when using passion flower as it does for any natural supplement: Read the product label and discuss with a doctor or other medical provider what dosage is suitable for you and your specific medical needs.
Be sure to tell them of any other medications or remedies you’re using, even if only occasionally. Passion flower may interact with other medications or affect how they work in your body.
As with most herbal remedies or other medications, it’s not a good idea to take passion flower if you are pregnant or breastfeeding.
As with any herbal remedy, there is always the possibility of interaction between passion flower and other treatments or medications.
There’s a fairly comprehensive list of medications known to have possible interactions with passion flower. These include:
Take care if you are taking blood thinners or anti-inflammatory medications, as these have been shown to have possible passion flower interactions.Other herbal remedies that may cause issues with passion flower arekavaand valerian root. Finally, alcohol, caffeine, and aspirin may not mix well with passion flower usage.
Passion flower on its own has not been associated with liver problems. However, one case report indicated that a combination of kava (which has been linked to liver problems) and passion flower led to a fatal liver injury.
RecapThe standard caveats apply to passion flower that apply to any other new medication or treatment: If you are already taking or planning to take another medication or supplement, consult with a qualified healthcare provider about potential interactions.
Recap
The standard caveats apply to passion flower that apply to any other new medication or treatment: If you are already taking or planning to take another medication or supplement, consult with a qualified healthcare provider about potential interactions.
Alternatives to Passion Flower
It’s important to remember that passion flower should not be used in place of other treatments for mental health or medical conditions. If passion flower isn’t working the way you need it to, or you want to try other options, there are other treatments and remedies that you might consider.
Other Herbal Supplements
Another option that many with depression have found helpful isSt. John’s Wort.Research suggests that St. John’s Wort is useful in treating mild to moderate depression, but its value as a treatment for anxiety is still not established.
Medication and Psychotherapy
If you have anxiety that causes distress and disruption in your life, talk to a healthcare professional for an appropriate diagnosis and treatment advice. Effective treatments are available that can help relieve anxiety, and those options should be your first line of defense before trying an alternative treatment such as passion flower.
Evidence-based treatments such as medication andcognitive-behavioral therapy(CBT) have been proven effective in reducing anxiety symptoms.Talk to your doctor about a referral to a qualified mental health professional for diagnosis and treatment.
Takeaways
Passion flower may have a number of benefits, including the relief of anxiety. However, more evidence is needed to support its use for this and other purposes. If you decide to try this herbal supplement, be aware of the potential side effects and talk to your doctor about any medications, substances, or supplements you are taking to avoid risky drug interactions.
Herbal Remedies for Anxiety and OCD
13 Sources
Verywell Mind uses only high-quality sources, including peer-reviewed studies, to support the facts within our articles. Read oureditorial processto learn more about how we fact-check and keep our content accurate, reliable, and trustworthy.
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